MDV3100: Tritium labeling at high specific activity
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- 作者：Chang Byona ; Sarvajit Chakravartyb ; Crist N. Filera ; ; Rajendra Jainc ; Mario P. Maniscalcoa
- 关键词：Androgen receptor ; MDV3100 ; Tritium ; Tritium NMR
- 刊名：Applied Radiation and Isotopes
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：108
- 期：Complete
- 页码：35-37
- 全文大小：588 K
文摘
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This paper describes the synthesis of [3H] MDV3100 by means of a Crabtree catalyst direct tritiaton.
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This paper also describes the characterization of [3H] MDV3100 means of proton and tritium NMR as well as mass spectrometry.
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