ST Elevation myocardial infarction in young adults: Prevalence, demographics, risk factor profile and early outcome after primary percutaneous coronary intervention

详细信息    查看全文

• 作者：Mehboob Ali Dar ; Akif Ali Mufti ; Yasir Beshir ; Hassan Khalaf ; Tariq I. Soomro ; Owayid AL Shammary ; Akram Desoky ; Mohammad Sayed ; Yasir Birema ; Mohammad Imran ; Arshad Sodhar ; Mushtaq Ahmad ; Fazel Ahmad
• 刊名：Journal of the Saudi Heart Association
• 出版年：2013
• 出版时间：April, 2013
• 年：2013
• 卷：25
• 期：2
• 页码：145
• 全文大小：46 K

文摘

Objectives

We sought to investigate prevalence, clinical profile,in-hospital and long term clinical outcomes of Primary Percutaneous Coronary Intervention in young adults presenting with Acute MI.

Methods

Total of 95 patients ?40 years were enrolled in retrospective data analysis.Prevalence,risk factor profile and demographics were analyzed. Procedural success,in-hospital and short-term (1 month) outcomes were assessed as primary end points.Secondary end-points were recurrent MI and new revascularization.

Results

Mean age was 36 ??#xA0;14 years (range 19-40); 97 % males and 3 % females. 59(62 % ) patients presented with anterior wall MI, 36(38 % ) with inferolateral wall MI; 5 % had infarction in other territories. 51 % patients were Saudis and 49 % were non Saudis.Risk factor profile revealed-Smoking (76 % ), Diabetes Mellitus (22 % ), Hypertension (20 % ), Dyslipidemia (12 % ), Family History (12 % ). 3 patients had cardiogenic shock at presentation. All underwent PPCI, with door to balloon time of 83 ??#xA0;05 min (74-220 min). Majority had SVD (47 % ). 2VD and 3VD was seen in 33 % and 18 % respectively. (Infarct related artery: LAD 54 % , RCA 23 % , LCX 12 % and Left Main Disease 2 % ). DES was deployed in 89 % . Successful recanalisation of IRA was achieved in 95 % with 87 % achieving TIMI III flow. No reflow occurred in 2 % . Procedure related coronary artery dissection occurred in 1 patient. 6 % developed Ventricular Tachycardia, 2 patients developed complete heart block. In-hospital mortality was 3 % . 1 patient had acute stent thrombosis and 4 patients presented with subacute and late stent thrombosis on follow up. All patients were alive at one-month follow up.

Conclusions

Our data reveal that younger patients, predominantly males comprise a significant proportion of patients of STEMI. Smoking appears to be a prominent risk factor. Such patients have a favorable outcome after Primary PCI. High incidence of stent thrombosis in our cohort of patients needs further assessment.