Phytochemical and cytotoxic studies on the roots of Euphorbia fischeriana

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• 作者：Qun Shi ; Yi-wei Sun ; Dali Meng ; ^{mengdl@163.com}
• 关键词：Euphorbia fischeriana ; Cytotoxic activities ; Diterpenoids ; Triterpenoids ; Pyrazine
• 刊名：Bioorganic & Medicinal Chemistry Letters
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：27
• 期：2
• 页码：266-270
• 全文大小：550 K
• 卷排序：27

文摘

9 compounds were isloated from the root of E. fischeriana including 3 new ones. 1 new compounds exhibited superior cytotoxic effects to that of positive on Hep-3B. 1 new and 1 known ones had stronger cytotoxic effects on A549 than that of 5-Fu. Two low-polarity fractions of E. Fischeriana showed moderate cytotoxic effects. Triterpenoid, abietane, tigliane might be the potential anti-tumor ingredients.