The impact of clinical parameters on progression-free survival of non-small cell lung cancer patients harboring EGFR-mutations receiving first-line EGFR-tyrosine kinase inhibitors
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- 作者：Yu-Mu Chen blackie@adm.cgmh.org.tw" class="auth_mail" title="E-mail the corresponding author ; Chien-Hao Lai sugun.ch@msa.hinet.net" class="auth_mail" title="E-mail the corresponding author ; Huang-Chih Chang kuan2101@adm.cgmh.org.tw" class="auth_mail" title="E-mail the corresponding author ; Tung-Ying Chao tychao@adm.cgmh.org.tw" class="auth_mail" title="E-mail the corresponding author ; Chia-Cheng Tseng cctseng@cloud.cgmh.org.tw" class="auth_mail" title="E-mail the corresponding author ; Wen-Feng Fang wenfengfang@yahoo.com.tw" class="auth_mail" title="E-mail the corresponding author ; Chin-Chou Wang ccwang5202@yahoo.com.tw" class="auth_mail" title="E-mail the corresponding author ; Yu-Hsiu Chung ma4227@ms31.hinet.net" class="auth_mail" title="E-mail the corresponding author ; Yi-Hsi Wang yihsi@cloud.cgmh.org.tw" class="auth_mail" title="E-mail the corresponding author ; Mao-Chang Su maochangsu@yahoo.com.tw" class="auth_mail" title="E-mail the corresponding author ; Kuo-Tung Huang jelly@cloud.cgmh.org.tw" class="auth_mail" title="E-mail the corresponding author ; Hung-cheng Chen chc1106@cloud.cgmh.org.tw" class="auth_mail" title="E-mail the corresponding author ; Meng-Chih Lin ; linmengchih@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Tyrosine-kinase inhibitors ; Epidermal growth factor receptor ; Non-small cell lung cancer ; Scoring system ; Progression-free survival
- 刊名：Lung Cancer
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：93
- 期：Complete
- 页码：47-54
- 全文大小：1216 K
文摘
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Prognostic factors for EGFRm NSCLC receiving first-line EGFR-TKIs are explored.
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Age, mutation, performance status and number of metastases are found to affect PFS.
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Blood lymphocyte to monocyte ratio also independently affect PFS.
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PFS score is created on a test dataset, and is validated on a validation dataset.
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