Design of nuclease-based target recycling signal amplification in aptasensors
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- 作者：Mengmeng Yana ; b ; Wenhui Baia ; b ; Chao Zhua ; b ; Yafei Huanga ; b ; c ; Jiao Yana ; b ; c ; Ailiang Chena ; b ; ailiang.chen@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Aptamer ; Aptasensors ; Nuclease ; Target recycling ; Signal amplification
- 刊名：Biosensors and Bioelectronics
- 出版年：2016
- 出版时间：15 March 2016
- 年：2016
- 卷：77
- 期：Complete
- 页码：613-623
- 全文大小：407 K
文摘
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Nuclease-based aptasensors show high sensitivity by target recycling signal amplification.
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Recent advances in nuclease-based aptasensors design were reviewed.
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The challenges and future perspectives were also proposed.