Resveratrol attenuates myocardial ischemia/reperfusion injury through up-regulation of vascular endothelial growth factor B

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• 作者：Lei Yang^a ; ^b ; ¹ ; Yan Zhang^a ; ¹ ; Mengmeng Zhu^a ; Qiong Zhang^c ; Xiaoling Wang^a ; Yanjiao Wang^a ; Jincai Zhang^a ; Jing Li^a ; Liang Yang^a ; Jie Liu^a ; Fei Liu^a ; Yinan Yang^a ; Licheng Kang^a ; Yanna Shen^c ; ^{shenyanna@sina.com} ; Zhi Qi^a ; ^{qizhi@nankai.edu.cn}
• 关键词：CK-MB ; creatine kinase isoenzyme ; DCFH-DA ; dichlorofluorescein diacetate ; +dp/dtmax ; maximal rate of increase of left ventricular pressure ; -dp/dtmax ; maximal rate of decrease of left ventricular pressure ; FBS ; fetal bovine serum ; IR ; ischemia/reperfusion ; K-H ; Krebs-Henseleit ; LV ; left ventricle ; LVDP ; left ventricular developed pressure ; LVEDP ; left ventricular end diastolic pressure ; mPTP ; mitochondrial permeability transition pore ; ROS ; reactive oxygen species ; RSV ; resveratrol ; TTC ; triphen
• 刊名：Free Radical Biology and Medicine
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：101
• 期：Complete
• 页码：1-9
• 全文大小：1761 K
• 卷排序：101

文摘

Resveratrol attenuates myocardial IR injury. Resveratrol up-regulated expression of VEGF-B during myocardial IR. Resveratrol inhibited generation of ROS during myocardial IR.