Use of a booster dose of capsular group C meningococcal glycoconjugate vaccine to demonstrate immunologic memory in children primed with one or two vaccine doses in infancy

详细信息    查看全文

• 作者：David Pace^a ; ^{dpace@go.net.mt} ; Ameneh Khatami^b ; Simon Attard-Montalto^a ; Merryn Voysey^c ; ^b ; Adam Finn^d ; Saul N. Faust^e ; ^f ; Paul T. Heath^g ; Ray Borrow^h ; Matthew D. Snape^b ; Andrew J. Pollard^b
• 关键词：Capsular group C N. meningitidis ; Immunologic memory ; MenC glycoconjugate vaccines ; MenC infant priming
• 刊名：Vaccine
• 出版年：2016
• 出版时间：7 December 2016
• 年：2016
• 卷：34
• 期：50
• 页码：6350-6357
• 全文大小：389 K
• 卷排序：34

文摘

Immunologic memory can be demonstrated by a MenC conjugate vaccine (MenCC) challenge. The immune response to a MenCC boost distinguishes primed from unprimed children. The type and number of MenCC doses used for infant priming affects immunologic memory.