Unlocking the Bacterial SecY Translocon
详细信息 查看全文
- 作者：Robin A. Corey1 ; William J. Allen1 ; Joanna Komar1 ; Simonas Masiulis1 ; Sam Menzies1 ; Alice Robson2 ; Ian Collinson1 ; ian.collinson@bristol.ac.uk" class="auth_mail" title="E-mail the corresponding author
- 刊名：Structure
- 出版年：2016
- 出版时间：5 April 2016
- 年：2016
- 卷：24
- 期：4
- 页码：518-527
- 全文大小：2359 K
文摘
- •
Validation of previously observed signal sequence-induced “unlocking” of SecYEG
- •
Conformational changes upon SecYEG unlocking are relayed to SecA binding site
- •
Unlocking the translocon perturbs the interaction between SecY and SecE
- •
Conformational changes distinct between secretion and membrane protein insertion