Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure
详细信息 查看全文
- 作者：Xuyu Qian1 ; 2 ; 18 ; Ha Nam Nguyen1 ; 3 ; 4 ; 18 ; Mingxi M. Song1 ; 9 ; Christopher Hadiono1 ; 10 ; Sarah C. Ogden11 ; Christy Hammack11 ; Bing Yao12 ; Gregory R. Hamersky5 ; Fadi Jacob1 ; Chun Zhong1 ; 4 ; Ki-jun Yoon1 ; 4 ; William Jeang1 ; 14 ; Li Lin12 ; Yujing Li12 ; Jai Thakor1 ; Daniel A. Berg1 ; Ce Zhang1 ; 4 ; Eunchai Kang1 ; 4 ; Michael Chickering1 ; David Nauen1 ; 6 ; Cheng-Ying Ho15 ; 16 ; Zhexing Wen1 ; 4 ; Kimberly M. Christian1 ; 4 ; Pei-Yong Shi17 ; Brady J. Maher5 ; 7 ; Hao Wu13 ; Peng Jin12 ; Hengli Tang11 ; Hongjun Song1 ; 3 ; 4 ; 8 ; shongju1@jhmi.edu" class="auth_mail" title="E-mail the corresponding author ; Guo-li Ming1 ; 3 ; 4 ; 7 ; 8 ; gming1@jhmi.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell
- 出版年：2016
- 出版时间：19 May 2016
- 年：2016
- 卷：165
- 期：5
- 页码：1238-1254
- 全文大小：9741 K
文摘
- listitem" id="list_ulist0010">
- •
A miniaturized spinning bioreactor for cost-effective culturing of organoids
- •
Generation of brain-region-specific organoids from human iPSCs
- •
ZIKV causes decrease of neuronal cell-layer volume resembling microcephaly
- •
Both African and Asian ZIKV infect neural progenitors in organoids