Gray matter volume alterations in first-episode drug-na茂ve patients with deficit and nondeficit schizophrenia
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- 作者：Wei Leia ; 1 ; Wei Denga ; 1 ; Mingli Lia ; Zongling Hea ; Yuanyuan Hana ; Chaohua Huanga ; Xiaohong Maa ; Qiang Wanga ; Wanjun Guoa ; Yinfei Lia ; Lijun Jianga ; Qiyong Gongb ; Xun Huc ; Nanyin Zhangd ; nuz2@psu.edu" class="auth_mail" title="E-mail the corresponding author ; Tao Lia ; xuntao26@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Deficit Schizophrenia ; Gray matter volume ; Voxel-based morphometry
- 刊名：Psychiatry Research: Neuroimaging
- 出版年：2015
- 出版时间：30 November 2015
- 年：2015
- 卷：234
- 期：2
- 页码：219-226
- 全文大小：982 K
文摘
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We examined gray matter volume changes in DS and NDS patients and their relatives.
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DS patients have less gray matter volume in left insula than NDS patients.
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Gray matter volume in left insula is associated with negative symptoms.
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Both DS patients and relatives have smaller cerebellar culmen than healthy controls.
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Gray matter change in left insula could be the biological marker of DS.
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