Characterization, prediction and evolution of plant peroxisomal targeting signals type 1 (PTS1s)
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- 作者：S. Reumanna ; b ; sigrun.reumann@uni-hamburg.de" class="auth_mail" title="E-mail the corresponding author ; G. Chowdharyb ; c ; gopal.chowdhary@uis.no" class="auth_mail" title="E-mail the corresponding author ; T. Lingnerd ; 1 ; thomas.lingner@biologie.uni-goettingen.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：AAC ; amino acid content ; AGT ; alanine-glyoxylate aminotransferase ; BD ; binding domain ; ER ; endoplasmic reticulum ; ERAD ; endoplasmic reticulum-associated decay ; IAA ; indole-3-acetic acid ; IBA ; indole-3-butyric acid ; PEG ; polyethylene glycol ; PEX ; peroxin ; PTS1/2 ; peroxisomal targeting signal type 1/2 ; ROS ; reactive oxygen species ; SAM ; sorting and assembly machinery ; TIC/TOC ; translocase at the inner and outer membrane of chloroplasts ; TIM/TOM ; translocase at the inner/outer membrane of mitochond
- 刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：1863
- 期：5
- 页码：790-803
- 全文大小：1193 K
文摘
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The functional plasticity of plant peroxisomes needs to be defined in greater detail.
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Recent quantitative, structural and mechanistic information of the interaction of PEX5 with PTS1 carrying proteins in relation to in vivo import efficiency are summarized.
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An overview of methodologies, capabilities and accuracies of available prediction algorithms for PTS1 carrying proteins is provided.
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A new model is presented in which order the two import pathways might have evolved in the ancient eukaryotic cell.