Mitochondrial dysfunction in bipolar disorder: Evidence, pathophysiology and translational implications
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- 作者：Giselli Scainia ; b ; Gislaine T. Rezinc ; Andre F. Carvalhod ; Emilio L. Streckb ; Michael Berke ; f ; Joã ; o Quevedoa ; g ; h ; i ; Joao.L.DeQuevedo@uth.tmc.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Mitochondria ; Bipolar disorder ; Mania ; Depression ; Mitochondrial dysfunction ; Oxidative stress ; Inflammation ; Apoptosis ; Neurogenesis
- 刊名：Neuroscience & Biobehavioral Reviews
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：68
- 期：Complete
- 页码：694-713
- 全文大小：2782 K
文摘
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Mitochondrial dysfunction affects neural development and neuronal functions.
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Mitochondrial abnormalities are common in bipolar disorder.
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Mitochondrial dysregulation leads to oxidative stress and inflammation.
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Mitochondria as a potential target of therapeutic interventions in bipolar disorder.