Bioactivities of n-hexane fraction of Vateria copallifera and GC-MS analysis of its phytoconstituents

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• 作者：Saroopa P. Samaradivakara^a ; ^{saroopa_s@yahoo.com} ; Radhika Samarasekera^b ; ^{radhika@iti.lk} ; L.M. Viranga Tillekeratne^c ; ^{ltillek@utnet.utoledo.edu} ; Shiroma M. Handunnetti^a ; ^{shiromah@ibmbb.cmb.ac.lk} ; O.V.D.S. Jagathpriya Weerasena^a ; ^{jagath@ibmbb.cmb.ac.lk} ; William R. Taylor^d ; ^{william.taylor3@utoledo.edu} ; Qasim Alhadidi^c ; ^{qasim.alhadidi@rockets.utoledo.edu} ; Zahoor A. Shah^c ; ^{zahoor.shah@utoledo.edu}
• 关键词：Vateria copallifera ; GC&ndash ; MS ; n-Hexane ; Bioactivities
• 刊名：Industrial Crops and Products
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：97
• 期：Complete
• 页码：87-92
• 全文大小：707 K
• 卷排序：97

文摘

Composition of n-hexane fraction of Vateria copallifera bark was identified for the first time by Gas chromatography–Mass spectrometry. N-Hexane fraction was found to be rich in hydrocarbon derivatives of undacane, decane and dodecane. Cytotoxicity, neuroprotection, nitric oxide inhibition, antioxidant and enzyme inhibitory activities were evaluated. Results indicated that the n-hexane fraction possess promising neuroprotective activity but weak cytotoxic, nitric oxide inhibitory antioxidant and enzyme inhibitory activity.