The Neurobiology of Postpartum Anxiety and Depression

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• 作者：Jodi L. Pawluski¹ ; ^{j.pawluski@gmail.com} ; ^{jodi-lynn.pawluski@univ-rennes1.fr} ; Joseph S. Lonstein² ; ^{lonstein@msu.edu} ; Alison S. Fleming³
• 关键词：postpartum depression ; perinatal depression ; anxiety ; maternal brain ; mothering ; maternal behavior
• 刊名：Trends in Neurosciences
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：40
• 期：2
• 页码：106-120
• 全文大小：2542 K
• 卷排序：40

文摘

Ten to twenty percent of postpartum women experience anxiety or depressive disorders, which can have detrimental effects on the mother, child, and family. Little is known about the neural correlates of these affective disorders when they occur in mothers, but they do have unique neural profiles during the postpartum period compared with when they occur at other times in a woman's life. Given that the neural systems affected by postpartum anxiety and depression overlap and interact with the systems involved in maternal caregiving behaviors, mother–infant interactions are highly susceptible to disruption. Thus, there is an intricate interplay among maternal mental health, the mother–infant relationship, and the neurobiological mechanisms mediating them that needs to be the focus of future study.