The Plasmodium alveolin IMC1a is stabilised by its terminal cysteine motifs and facilitates sporozoite morphogenesis and infectivity in a dose-dependent manner

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• 作者：Fatimah S. Al-Khattaf¹ ; Annie Z. Tremp ; Amira El-Houderi² ; Johannes T. Dessens ; ^{Johannes.Dessens@lshtm.ac.uk}
• 关键词：Alveolin ; Intermediate filament ; Cytoskeleton ; Palmitoylation ; Sporozoite ; Plasmodium berghei
• 刊名：Molecular and Biochemical Parasitology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：211
• 期：Complete
• 页码：48-56
• 全文大小：1605 K
• 卷排序：211

文摘

The terminal cysteine motifs of the alveolin IMC1a stabilise the protein. IMC1a depletion dose-dependently affects sporozoite morphogenesis. Sporozoite size correlates with sporozoite infectivity.