刊名:Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
出版年:2017
出版时间:February 2017
年:2017
卷:1865
期:2
页码:165-175
全文大小:1948 K
卷排序:1865
文摘
The βα and αβ modules of TIM barrel proteins were clustered based on structure and sequence. A number of recurring motifs have been identified. A chimeric protein A0 was created by using the recurring motifs as interfaces. A0 was significantly improved by six rounds of directed evolution.