Quantitative Dixon MRI sequences to relate muscle atrophy and fatty degeneration with range of motion and muscle force in brachial plexus injury

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• 作者：Bouke J. Duijnisveld^a ; ^{b.j.duijnisveld@lumc.nl} ; Jan Ferdinand Henseler^a ; Monique Reijnierse^b ; Marta Fiocco^c ; ^d ; Hermien E. Kan^e ; Rob G.H.H. Nelissen^a
• 关键词：BPI ; brachial plexus injury ; CSA ; cross sectional area ; CT ; computed tomography ; DASH ; disability of the arm ; shoulder and hand questionnaire ; FOV ; field of view ; ICC ; intraclass correlation coefficient ; MR ; magnetic resonance ; MRC ; medical research council scale ; ROI ; region of interest ; ST-36 ; short form-36 ; TE ; echo time ; TR ; repetition time ; TSE ; turbo spin echo ; VAS ; visual analogue score
• 刊名：Magnetic Resonance Imaging
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：36
• 期：Complete
• 页码：98-104
• 全文大小：626 K
• 卷排序：36

文摘

Assessment of muscle atrophy and fatty degeneration in brachial plexus injury (BPI) could yield valuable insight into pathophysiology and could be used to predict clinical outcome. The objective of this study was to quantify and relate fat percentage and cross-sectional area (CSA) of the biceps to range of motion and muscle force of traumatic brachial plexus injury (BPI) patients.MethodsT1-weighted TSE sequence and three-point Dixon images of the affected and non-affected biceps brachii were acquired on a 3 Tesla magnetic resonance scanner to determine the fat percentage, total and contractile CSA of 20 adult BPI patients. Regions of interest were drawn by two independent investigators to determine the inter-observer reliability. Paired Students' t-test and multivariate analysis were used to relate fat percentage, total and contractile CSA to active flexion and biceps muscle force.ResultsThe mean fat percentage 12 ± 5.1% of affected biceps was higher than 6 ± 1.0% of the non-affected biceps (p < 0.001). The mean contractile CSA 8.1 ± 5.1 cm2 of the affected biceps was lower than 19.4 ± 4.9 cm2 of the non-affected biceps (p < 0.001). The inter-observer reliability was excellent (ICC 0.82 to 0.96). The contractile CSA contributed most to the reduction in active flexion and muscle force.ConclusionQuantitative measurement of fat percentage, total and contractile CSA using three-point Dixon sequences provides an excellent reliability and relates with active flexion and muscle force in BPI.