Ultrasonic-assisted extraction condition was optimized by RSM.
Maximum extraction yield of 5.49% was obtained under the optimal extraction condition.
A purified polysaccharide with molecular weight of 3.26 × 105 Da was obtained.
PPS was characterized as (1 → 6)-α-d-glucan by instrumental analysis.
PPS exhibited antitumor activity in vitro on HepG-2 and BGC-823 cells.