A reevaluation of the possibility and characteristics in bipolar mania with mixed features: A retrospective chart review

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• 作者：In Hee Shim ; Young Sup Woo ; Tae-Youn Jun ; Won-Myong Bahk
• 关键词：Bipolar disorder ; Mixed feature ; Mixed mania ; Cincinnati criteria ; Clinical characteristics
• 刊名：Psychiatry Research
• 出版年：28 February, 2014
• 年：2014
• 卷：215
• 期：2
• 页码：335-340
• 全文大小：328 K

文摘

The aim of the present study was to reevaluate the feasibility of diagnosing a mixed features behind bipolar mania and to elucidate the clinical characteristics, treatment response, and course of the illness throughout a 12-month follow-up. The subjects (n=171) were inpatients diagnosed with bipolar I disorder, manic, between 2003 and 2010 and were classified into three groups: 鈥渕ania鈥?(n=67), 鈥渕ania with聽probable mixed features鈥?(n=79), and 鈥渕ania with聽definite mixed features鈥?(n=25). Diagnoses were in accordance with the Cincinnati criteria, which include the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, Text Revision characteristics for a major depressive episode, except for agitation and insomnia. The charts of subjects were retrospectively reviewed for demographic and clinical characteristics prior to the index episode, clinical data regarding the index episode, and treatment courses over a 12-month follow-up period. Subjects in the mania with definite mixed features were more likely to be young at admission, to be female, to have a familial affective loading, and to have a history of suicidality relative to the mania. The results of the present study suggest the need for regular assessment of symptoms associated with both polarities during an episode in routine practice.