Molecular identification and comparative transcriptional analysis of myxovirus resistance GTPase (Mx) gene in goose (Anser cygnoide) after H9N2 AIV infection
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- 作者：Miao Zenga ; 1 ; Shun Chena ; b ; c ; 1 ; shunchen@sicau.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Mingshu Wanga ; b ; c ; Renyong Jiaa ; b ; c ; Dekang Zhub ; c ; Mafeng Liua ; Kunfeng Suna ; b ; c ; Qiao Yanga ; b ; c ; Ying Wua ; b ; c ; Xiaoyue Chenb ; c ; Anchun Chenga ; b ; c ; chenganchun@vip.163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Goose ; Mx ; Molecular cloning ; Tissue distribution profile ; H9N2 AIV
- 刊名：Comparative Immunology, Microbiology and Infectious Diseases
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：47
- 期：Complete
- 页码：32-40
- 全文大小：2123 K
文摘
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This is the first report on cDNA of myxovirus resistance GTPases (Mx) in goose.
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The goMx shares partly conserved exons in mRNA and highly conserved domains in primary structure with other homologues.
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The residues at the 629 aa and 142 aa of goMx might affect the antiviral activity.
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The mRNA transcriptions of goMx in goose PBMCs, healthy and AIV-infected goslings were studied.