- 作者：Akinori Sairaku ; Yukihiko Yoshida ; Haruo Hirayama ; Yukiko Nakano ; Mamoru Nanasato ; Hiroki Kamiya ; Noriaki Kondo ; Yasuki Kihara
- 关键词：Ablation ; Atrial fibrillation ; Portable monitor ; Respiratory disturbance index ; SD-101 ; Sedation ; Sleep-disordered breathing
- 刊名：Sleep Medicine
- 出版年：2013
- 出版时间：July, 2013
- 年：2013
- 卷：14
- 期：7
- 页码：622-627
- 全文大小：939 K
Background
Sleep-disordered breathing (SDB) frequently is induced by sedation during ablation of atrial fibrillation (AF). We tested whether or not sedative-induced SDB is associated with clinical sleep apnea syndrome (SAS).Methods
We examined SDB observed during intra-ablation sedation with a novel portable respiratory monitor (PM), SD-101, in 140 patients undergoing AF ablation without any known SAS. A sleep study was repeated the next night of the ablation with the simultaneous use of the SD-101 and type 3 PM, APNOMONITOR V.
Results
The respiratory disturbance index (RDI) during sedation (20.0 ¡À 7.8 events/h) was significantly correlated with the RDI measured by the SD-101 during the night (15.8 ¡À 13.7 events/h; r = 0.50) and the RDI assessed by the APNOMONITOR V during the night (12.7 ¡À 12.3 events/h; r = 0.55). An excellent agreement was found between the RDIs simultaneously measured with the 2 PMs (intraclass correlation coefficient, 0.84), especially for an RDI of ?30 events/h (¦Ê statistic value, 0.82). The area under the receiver-operating characteristic curve for the RDI with the use of the SD-101 during sedation to identify the patients with an RDI of ?30 events/h by both PMs during the night was 0.92. A left atrial diameter of >40 mm (odds ratio [OR], 4.10) and an RDI during sedation of >20 events/h (OR, 17.75) were independently associated with having an RDI of ?30 events/h with both PMs during the night.
Conclusions
Frequent episodes of sedative-induced SDB may have a diagnostic value for SAS in patients with AF.