Anti-obesity effects of Asian dayflower, Commelina communis, in mice with high-fat diet-induced obesity and in 3T3-L1 cells
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- 作者：Shiori Nagaia ; Eri Wakaia ; Makio Shibanob ; Ko Fujimoria ; fujimori@gly.oups.ac.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：C/EBP ; CCAAT/enhancer-binding protein ; PPAR ; peroxisome proliferator-activated receptor ; GLUT ; glucose transporter ; CCT ; C.&thinsp ; communis tea ; WAT ; white adipose tissue ; HFD ; high-fat diet ; LFD ; low-fat diet ; qPCR ; quantitative PCR ; TBP ; TATA-binding protein ; NEFA ; non-esterified fatty acid ; ITT ; insulin tolerance test ; MS ; mass spectrometry ; UHPLC ; ultra-HPLC ; DMEM ; Dulbecco's modified Eagle's medium ; 2-NBDG ; 2-deoxy-2-[(7-nitro-2 ; 1 ; 3-benzoxadiazol-4-yl)amino]-D-glucose ; vWAT ; visceral WAT ; s
- 刊名：Journal of Functional Foods
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：22
- 期：Complete
- 页码：490-503
- 全文大小：1128 K
文摘
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Asian dayflower, Commelina communis tea (CCT), decreased the body weight gain in mice.
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CCT lowered the serum glucose and triglyceride levels.
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20">CCT slightly improved insulin sensitivity.
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25">Glucoluteolin, a major flavonoid of C. communis, reduced the intracellular triglyceride level.
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Glucoluteolin repressed the expression of the GLUT4 and glucose uptake in 3T3-L1 cells.