Polycyclic aromatic hydrocarbons exposure and lung function decline among coke-oven workers: A four-year follow-up study
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- 作者：Suhan Wanga ; Yansen Baia ; Qifei Denga ; Zhuowang Chena ; Juanxiu Daia ; Xiaoliang Lia ; Wangzhen Zhangb ; Xiaomin Zhanga ; Meian Hea ; Tangchun Wua ; Huan Guoa ; ghuan5011@hust.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：FVC ; forced vital capacity ; FEV1 ; forced expiratory volume in one second ; FEF25&ndash ; 75 ; forced expiratory flow between 25% and 75% of vital capacity ; OHNa ; hydroxynaphthalene ; OHFlu ; hydroxyfluorene ; OHPh ; hydroxyphenanthrene ; 1-OHP ; 1-hydroxypyrene ; 6-OHChr ; 6-hydroxychrysene ; 3-OHBaP ; 3-hydroxybenzo[a]pyrene ; ΣOH-PAHs ; total concentration of urinary monohydroxy PAHs ; LOD ; limits of detection ; COEs ; coke-oven emissions
- 刊名：Environmental Research
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：150
- 期：Complete
- 页码：14-22
- 全文大小：679 K
文摘
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We explored the impact of PAHs exposure on lung function in the cohort design.
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Certain and total PAHs lead to accelerated declines in FEV1/FVC and FEF25-75.
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A 10-fold increase in urinary ΣOH-PAHs was associated with a 2.90% accelerated decline in FEV1/FVC.
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A 10-fold increase in urinary ΣOH-PAHs was associated with a 292.91 mL accelerated decline in FEF25-75.