Hippocampal neurogenesis response: What can we expect from two different models of hypertension?
详细信息 查看全文
- 作者：Daniela Pedrosoa ; 1 ; Ana R. Nunesa ; 1 ; Lucí ; lia N. Diogoa ; Carole Oudotb ; Emí ; lia C. Monteiroa ; Catherine Brennerb ; Helena L.A. Vieiraa ; c ;
- 关键词：CIH ; chronic intermittent hypoxia ; DG ; dentate gyrus ; DOCA ; deoxycorticosterone acetate ; DSS ; Dahl salt-sensitive ; IH ; Intermittent hypoxia ; OSA ; obstructive sleep apnea ; SGZ ; subgranular zone ; SHR ; spontaneous hypertensive rats ; SVZ ; subventricular zone
- 刊名：Brain Research
- 出版年：2016
- 出版时间：1 September 2016
- 年：2016
- 卷：1646
- 期：Complete
- 页码：199-206
- 全文大小：1663 K
文摘
- •
Assessment of hippocampal neurogenesis in two hypertension models: DSS and CIH.
- •
CIH hypertension model exhibits decreased neuronal markers and increased astrogliosis.
- •
CIH increases Ki67 expression, suggesting cell proliferation in Dentate Gyrus.
- •
Neuronal expression of Nestin increases in Dentate Gyrus from CIH rats.
- •
Intermittent hypoxia modulates neurogenesis.