Identification of pathogenic factors potentially involved in Staphylococcus aureus keratitis using proteomics
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- 作者：Shamila Khana ; b ; Nerida Colea ; b ; Emma B.H. Humea ; b ; Linda L. Garthwaiteb ; Terry Nguyen-Khuonga ; c ; Bradley J. Walshc ; Mark D.P. Willcoxa ; b ; m.willcox@unsw.edu.au" class="auth_mail" title="E-mail the corresponding author
- 关键词：Staphylococcus aureus ; Proteomics ; Keratitis
- 刊名：Experimental Eye Research
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：151
- 期：Complete
- 页码：171-178
- 全文大小：938 K
文摘
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The cell-associated or extracellular proteomes of two strains of S. aureus were compared.
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The virulent strain produced more potential virulence factors in both proteomes, including fibronecin-binding protein.
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The virulent strain was able to bind to ligands of these adhesins in greater numbers than the less virulent strain.
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The differences in proteomes of strains of S. aureus correlate to different degrees of virulence in corneal infections.