NLRC5 regulates cell proliferation, migration and invasion in hepatocellular carcinoma by targeting the Wnt/β-catenin signaling pathway
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- 作者：Yun-yun Penga ; b ; 1 ; Ying-hua Hea ; c ; d ; 1 ; Chen Chena ; c ; d ; Tao Xua ; c ; d ; Lin Lia ; e ; Ming-ming Nia ; c ; d ; Xiao-ming Menga ; c ; d ; Cheng Huanga ; c ; d ; Jun Lia ; c ; d ; lj@ahmu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; ahmupengyunyun@sina.con" class="auth_mail" title="E-mail the corresponding author
- 关键词：NLRC5 ; HCC ; β-catenin ; Wnt/β-catenin signaling pathway ; Therapeutic
- 刊名：Cancer Letters
- 出版年：2016
- 出版时间：28 June 2016
- 年：2016
- 卷：376
- 期：1
- 页码：10-21
- 全文大小：2979 K
文摘
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The role of NLRC5 in hepatocellular carcinoma cell proliferation, migration and invasion capacities.
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Knockdown of NLRC5 significantly inhibits the tumor formation in nude mice.
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NLRC5 interacts with the activation of Wnt/β-catenin signaling pathway in HCC.