Biological and structural analyses of bovine heparin fractions of intermediate and high molecular weight

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• 作者：Alexsandro V. Nogueira ; Daiana L. Drehmer ; Marcello Iacomini ; Guilherme L. Sassaki ; Thales R. Ciprianip> ; p>p>trcipriani@ufpr.brp>p> ; p>p>trcipriani@hotmail.comp>
• 关键词：Bovine heparin ; Ultrafiltration ; Anticoagulant activity ; Venous thrombosis
• 刊名：Carbohydrate Polymers
• 出版年：2017
• 出版时间：10 February 2017
• 年：2017
• 卷：157
• 期：Complete
• 页码：72-78
• 全文大小：1248 K
• 卷排序：157

文摘

Ultrafiltration can be used to fractionate bovine heparin (BH). BH fractions with different molecular weights have different anticoagulant activity. Native structural differences can influence the activity of BH fractions. BH fractions with different molecular weights have similar antithrombotic effects.