High expression of orphan nuclear receptor NR4A1 in a subset of ovarian tumors with worse outcome
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- 作者：Evan Delgadoa ; 1 ; Michelle M. Boisenb ; 1 ; boockmeiermm@mail.magee.edu" class="auth_mail" title="E-mail the corresponding author ; Robin Laskeyb ; 1 ; 2 ; Rui Chenc ; 3 ; Chi Songc ; 4 ; Jad Sallitd ; Zachary A. Yochume ; Courtney L. Andersenf ; g ; Matthew J. Sikoraf ; Jacob Wagnera ; Stephen Safeh ; Esther Elishaevi ; Adrian Leef ; Robert P. Edwardsb ; Paul Haluskaj ; 5 ; George Tsengc ; 1 ; Mark Schurdaka ; 1 ; Steffi Oesterreichf ; 1
- 关键词：Ovarian cancer ; Nuclear receptors ; Therapeutic target
- 刊名：Gynecologic Oncology
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：141
- 期：2
- 页码：348-356
- 全文大小：1705 K
文摘
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Nuclear receptors play a role in development and progression of several cancers.
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NR4A1expression is predictive of outcomes in ovarian cancer patients.
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NR4A1 a potential driver of pathogenesis in ovarian cancer.