The Nuclear Factor 魏B pathway: A link to the immune system in the radiation response
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- 作者：Christine E. Hellweg ; christine.hellweg@dlr.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：Nuclear Factor 魏B ; Immune system ; Cellular radiation response ; Linear energy transfer ; Bystander effect ; Chemokines
- 刊名：Cancer Letters
- 出版年：2015
- 出版时间：28 November 2015
- 年：2015
- 卷：368
- 期：2
- 页码：275-289
- 全文大小：838 K
文摘
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ATM and NEMO are the nucleoplasmic shuttles for NF-魏B activation by ionizing radiation.
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Cytokine expression can sustain NF-魏B activation in a positive feed forward loop.
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Danger signals can activate NF-魏B via Toll-like receptors.
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NF-魏B is a central element in radiation-induced bystander effects.