Anti-hypoxia activity and related components of Rhodobryum giganteum Par.
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- 作者：Ying Cai<sup>asup> ; Yu Lu<sup>bsup> ; Ruihua Chen<sup>asup> ; Qunli Wei<sup>asup> ; Xiaohe Lu<sup>asup><sup> ; sup><sup>Luxiaohecaiying@126.comsup>
- 关键词：Rhodobryum giganteum ; Anti-hypoxia ; Active components ; Cardiovascular disease
- 刊名：Phytomedicine
- 出版年：2011
- 出版时间：15 January 2011
- 年：2011
- 卷：18
- 期：2-3
- 页码：224-229
- 全文大小：191 K
文摘
Different extracts of Rhodobryum giganteum Par. were screened with mice model of acute myocardial hypoxia induced by isoproterenol and pituitrin, eight compounds, i.e. p-hydroxycinnamic acid, caffeic acid-4-O-β-d-glucopyranoside, salicin, 7,8-dihydroxy coumarin, menthol, allantoin, palmitic acid, palmitamide were isolated and identified from the active fraction, among which p-hydroxycinnamic acid and 7,8-dihydroxy coumarin were confirmed having protective effects on myocardial hypoxia-reoxygenation injury, suggesting that these two components were major active ingredients of R. giganteum for cardiovascular disease.