Oleuropein aglycone in lipid bilayer membranes. A molecular dynamics study
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- 作者：Vicente Galianoa ; José ; Villalaí ; nb ; jvillalain@umh.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：Chol ; cholesterol ; OA ; oleuropein aglycone ; OLE ; oleuropein ; POPC ; 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine ; POPG ; 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1&prime ; -rac-glycerol)
- 刊名：Biochimica et Biophysica Acta (BBA)-Biomembranes
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：1848
- 期：11
- 页码：2849-2858
- 全文大小：1842 K
文摘
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We simulate the unbiased atomic detail of oleuropein aglycone in a lipid bilayer.
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Oleuropein aglycone locates in the palisade structure of the membrane.
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Oleuropein aglycone is located in a deep position in POPC/POPG/Chol.
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Oleuropein aglycone specifically affects negatively-charged phospholipids.