Psychiatric disorders and symptoms severity in pre-school children with cow's milk allergy

详细信息    查看全文

• 作者：E. Topal^a ; ^{erdemtopal44@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; F. Catal^a ; N. Soylu^b ; O.O. Ozcan^b ; M.H. Celiksoy^c ; A. Babayiğit^d ; D. Erge^e ; H.T.E. Karakoç ; ^a ; R. Sancak^c
• 关键词：Attention deficit hyperactivity disorder ; Attachment disorder ; Cow's milk allergy ; ECI-4 ; Oppositional defiant disorder
• 刊名：Allergologia et Immunopathologia
• 出版年：2016
• 出版时间：September-October 2016
• 年：2016
• 卷：44
• 期：5
• 页码：445-449
• 全文大小：498 K

文摘

Psychiatric disorders are seen frequently in atopic diseases. The present study aims to evaluate the frequency of psychiatric disorders and the severity of psychiatric symptoms in pre-school children with cow's milk allergy.

Methods

The parents of the pre-school children with cow's milk allergy were interviewed in person and asked to fill out the Early Childhood Inventory-4 form.

Results

The cow's milk allergy group included 40 children (27 male, 13 female) with mean age, 44.5 ± 14.7 months, and the control group included 41 children (25 male, 16 female) with mean age, 47.6 ± 15.2 months. It was established that 65% of the group with cow's milk allergy received at least one psychiatric diagnosis, while 36.6% of the control group received at least one psychiatric diagnosis, with a statistically significant difference (p = 0.02). Within the psychiatric disorders, attention deficit hyperactivity disorders (odds ratio: 4.9, 95% CI: 1.472–16.856, p = 0.006), oppositional defiant disorder (odds ratio: 5.6, 95% CI: 1.139–28.128, p = 0.026), and attachment disorder (odds ratio: 4.8, 95% CI: 1.747–13.506, p = 0.004) were found significantly higher compared with the healthy control group. When the groups were compared in terms of psychiatric symptom severity scores, calculated by using the Early Childhood Inventory-4 form, attention deficit hyperactivity disorders severity (p = 0.006) and oppositional defiant disorder severity (p = 0.037) were found to be higher in the cow's milk allergy group.

Conclusion

Psychiatric disorders are frequent and severe in pre-school children with cow's milk allergy.