Will cardiac optogenetics find the way through the obscure angles of heart physiology?

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• 作者：Nicola Pianca^a ; ^b ; ¹ ; ^{marco.mongillo@unipd.it} ; Tania Zaglia^a ; ^b ; ¹ ; Marco Mongillo^a ; ^b ; ^c ;
• 关键词：Cardiac optogenetics ; Channelrhodopsin-2 ; Cardiac arrhythmias ; Heart physiology
• 刊名：Biochemical and Biophysical Research Communications
• 出版年：2017
• 出版时间：22 January 2017
• 年：2017
• 卷：482
• 期：4
• 页码：515-523
• 全文大小：1460 K
• 卷排序：482

文摘

Optogenetics enables non-invasive control of specific excitable cells in vivo. Cardiac optogenetics is useful to study the physiology of myocardial cell subsystems. Cardiac optogenetics has been applied in preclinical research of arrhythmogenesis. Gene manipulation and technical advancements near cardiac optogenetics to therapy.