Alterations in oviductal cilia morphology and reduced expression of axonemal dynein in diabetic NOD mice

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• 作者：Stephanie L. Shorter ; Ahmad J.H. Albaghdadi ; Frederick W.K. Kan ; ^{kanfwk@queensu.ca}
• 关键词：Oviductal cilia ; Axonemal dynein ; Type 1 diabetes ; Female NOD mice
• 刊名：Tissue and Cell
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：48
• 期：6
• 页码：588-595
• 全文大小：4406 K
• 卷排序：48

文摘

Cilia and expression of DNAI2 were examined in oviducts of female NOD mice. Oviductal cilia of diabetic NOD mice appeared to be reduced in number. Expression of DNAI2 protein was significantly less in oviducts of diabetic NOD mice. Oviductal cilia of diabetic NOD mice displayed abnormal axonemal ultrastructure. Altered oviductal cilia in diabetic mice might be detrimental to ciliary functions.