Reductive ipso-radical cyclization onto aromatic rings of five-membered alicyclic amino acids bearing N-(2-phenyl)benzoyl groups by photoinduced electron transfer promoted decarboxylation

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• 作者：Tomoaki Yamada ; Yui Ozaki ; Mugen Yamawaki ; Yoshihiko Sugiura ; Kana Nishino ; Toshio Morita ; Yasuharu Yoshimi ; ^{yyoshimi@u-fukui.ac.jp}
• 关键词：Reductive ipso-radical cyclization ; Spiro dihydroisoquinolinone ; Five-membered alicyclic amino acid ; N-(2-phenyl)benzoyl group ; Photoinduced decarboxylation
• 刊名：Tetrahedron Letters
• 出版年：2017
• 出版时间：1 March 2017
• 年：2017
• 卷：58
• 期：9
• 页码：835-838
• 全文大小：649 K
• 卷排序：58

文摘

Reductive ipso-radical cyclization onto benzene ring by alkyl radical is achieved. Substrates are limited to five-membered aliphatic carboxylic acids. Tetracyclic spiro dihydroisoquinolinones can be prepared in one-step.