Decreased gray matter volume is associated with the subtypes of psychotic symptoms in patients with antipsychotic-naïve mild or moderate Alzheimer's disease: A voxel-based morphometry study
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- 作者：Young-Min Leea ; b ; Young-In Chungc ; yichung@pusan.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Je-Min Parka ; b ; Byung-Dae Leea ; b ; Eunsoo Moona ; b ; Hee-Jeong Jeonga ; b ; Ji-Hoon Kimc ; Hak-Jin Kimd ; Chi-Woong Mune ; Tae-Hyung Kime ; Young-Hoon Kimf ; Eun-Joo Kimg
- 关键词：Alzheimer's disease ; The subtypes of psychotic symptoms ; The gray matter volumes
- 刊名：Psychiatry Research: Neuroimaging
- 出版年：2016
- 出版时间：30 March 2016
- 年：2016
- 卷：249
- 期：Complete
- 页码：45-51
- 全文大小：563 K
文摘
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The purpose of this study was to investigate the association between gray matter volume and two subtypes of psychotic symptoms, namely paranoid and misidentification subtypes, in antipsychotic-naïve mild or moderate AD patients.
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Misidentification subtype compared with non-psychosis group showed more significantly decreased gray matter volume.
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Misidentification subtype compared with paranoid subtype showed more significantly decreased gray matter volume.
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Non-psychosis group compared with paranoid subtype showed more significantly decreased gray matter volume.
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These results suggest that misidentification, paranoid subtype and non-psychosis group have distinct neural correlate.