PARK16 polymorphisms, interaction with smoking, and sporadic Parkinson's disease in Japan
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- 作者：Yoshihiro Miyakea ; miyake.yoshihiro.ls@ehime-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Keiko Tanakaa ; Wakaba Fukushimab ; Chikako Kiyoharac ; Satoshi Sasakid ; Yoshio Tsuboie ; Tomoko Oedaf ; Hiroyuki Shimadag ; Nobutoshi Kawamurah ; Nobutaka Sakaei ; Hidenao Fukuyamaj ; Yoshio Hirotak ; Masaki Nagail ; Yoshikazu Nakamuram ; Fukuoka Kinki Parkinson's Disease Study Group1
- 关键词：Case&ndash ; control study ; Gene&ndash ; environment interaction ; Japanese ; Parkinson's disease ; Smoking ; PARK16 polymorphisms
- 刊名：Journal of the Neurological Sciences
- 出版年：2016
- 出版时间：15 March 2016
- 年：2016
- 卷：362
- 期：Complete
- 页码：47-52
- 全文大小：243 K
文摘
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PARK16 SNPs rs823128, rs947211, and rs823156 were significantly associated with PD.
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Three haplotypes were significantly related to PD.
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The additive interaction between SNP rs823156 and smoking was significant.