Nipbl Interacts with Zfp609 and the Integrator Complex to Regulate Cortical Neuron Migration

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• 作者：Debbie L.C. van den Berg¹ ; ^{debbie.vandenberg@crick.ac.uk} ; Roberta Azzarelli¹ ; Koji Oishi¹ ; Ben Martynoga¹ ; Noelia Urb&aacute ; n¹ ; Dick H.W. Dekkers² ; Jeroen A. Demmers² ; Fran&ccedil ; ois Guillemot¹ ; ³ ; ^{francois.guillemot@crick.ac.uk}
• 关键词：Nipbl ; Zfp609 ; Cornelia de Lange syndrome ; Integrator ; neuronal migration ; transcription ; RNA pol2 pausing
• 刊名：Neuron
• 出版年：2017
• 出版时间：18 January 2017
• 年：2017
• 卷：93
• 期：2
• 页码：348-361
• 全文大小：4172 K
• 卷排序：93

文摘

Nipbl interacts with the transcription factor Zfp609 and the Integrator complex Nipbl, Zfp609, and Integrator are required for cortical neuron migration Nipbl, Zfp609, and Integrator co-occupy genomic binding sites independently of cohesin Nipbl, Zfp609, and Integrator directly regulate neuronal migration genes