Revisiting Management of Pediatric Brain Tumors with New Molecular Insights

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• 作者：Wafik Zaky¹ ; ^{wzaky@mdanderson.org" class="auth_mail" title="E-mail the corresponding author}
• 刊名：Cell
• 出版年：2016
• 出版时间：25 February 2016
• 年：2016
• 卷：164
• 期：5
• 页码：844-846
• 全文大小：506 K

文摘

Pediatric central nervous system primitive neuro-ectodermal brain tumors (CNS-PNETs) are rare tumors with ill-defined biological features. In this issue of Cell, Sturm et al. used state-of-the-art methods to interrogate these tumors' biology. Their integrated molecular analyses led them to propose a new molecular classification, with four new entities identified, that should get oncologists' attention.