Oxidative stress induces claudin-2 nitration in experimental type 1 diabetic nephropathy
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- 作者：Eduardo Molina-Jijó ; na ; Rafael Rodrí ; guez-Muñ ; oza ; Marí ; a del Carmen Namoradoa ; José ; Pedraza-Chaverrib ; José ; L. Reyesa ; jreyes@fisio.cinvestav.mx" class="auth_mail
- 关键词：Renal tight junctions ; Oxidative stress ; Claudins ; Protein tyrosine nitration ; Glucose transporters ; Free radicals
- 刊名：Free Radical Biology and Medicine
- 出版年：July 2014
- 年：2014
- 卷：72
- 期：Complete
- 页码：162-175
- 全文大小：12149 K
文摘
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Superoxide anion production is increased in early development of diabetic nephropathy.
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Diabetes causes disruption of renal tight junctions.
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Renal claudin-2 nitration is present in the early stage of diabetes.
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Glucose transporters are overexpressed in the initial establishment of diabetes.