Structural characterization and effect on anti-angiogenic activity of a fucoidan from Sargassum fusiforme
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- 作者：Qifei Cong1 ; Huanjun Chen1 ; Wenfeng Liao ; Fei Xiao ; Peipei Wang ; Yi Qin ; Qun Dong ; dongqun@simm.ac.cn" class="auth_mail" title="E-mail the corresponding author ; Kan Ding ; dingkan@simm.ac.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Sargassum fusiforme ; Fucoidan ; Structure ; Anti-angiogenic activity
- 刊名：Carbohydrate Polymers
- 出版年：2016
- 出版时间：20 January 2016
- 年：2016
- 卷：136
- 期：Complete
- 页码：899-907
- 全文大小：2378 K
文摘
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A fucoidan from Sargassum fusiforme was isolated and characterized.
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Backbone was alternate 1,2-linked α-d-Manp and 1,4-linked β-d-GlcpA.
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Branches contain fucose, xylose, galactose, glucuronic acid and sulfate group.
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Fucoidan could significantly inhibit the tube formation.
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Oligosaccharide fractions exhibited the anti-angiogenesis activities.