Molecular characterization and function of a PTEN gene from Litopenaeus vannamei after Vibrio alginolyticus challenge
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- 作者：C.-y. Xie ; J.-r. Kong ; C.-s. Zhao ; Y.-c. Xiao ; T. Peng ; Y. Liu ; W.-n. Wang ; weina63@aliyun.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：LvPTEN ; Litopenaeus vannamei ; Vibrio alginolyticus ; RNAi ; Apoptosis ; Shrimp immunity
- 刊名：Developmental & Comparative Immunology
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：59
- 期：Complete
- 页码：77-88
- 全文大小：3330 K
文摘
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A crustacean PTEN gene (LvPTEN) was identified in Litopenaeus vannamei.
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LvPTEN is distributed in both cytoplasm and nucleus.
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The transcription of LvPTEN after Vibrio alginolyticus challenge indicated that it is involved in pathogen infection.
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LvPTEN may participate in the regulation of apoptosis via the PI3K/AKT signaling pathway.
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LvPTEN may play an important role in shrimp innate immunity.
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