A general method for synthesis of cis-dicarbonyl epoxides through DBU/LiBr-cocatalyzed cyclization of α,β-dicarbonyl peroxides
详细信息 查看全文
- 作者：Zhenzhen Zong ; Xiaohui Bai ; Shenglin Lu ; Zhiping Li ; zhipingli@ruc.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Peroxide ; Epoxide ; Cyclization ; Disatereoselectivity ; Cocatalysis
- 刊名：Tetrahedron Letters
- 出版年：2016
- 出版时间：24 August 2016
- 年：2016
- 卷：57
- 期：34
- 页码：3827-3831
- 全文大小：2877 K
文摘
- •
A general method for synthesis of cis-dicarbonyl epoxides is developed.
- •
The diastereoselective cyclization of α,β-dicarbonyl peroxides is achieved by DBU/LiBr cocatalysis.
- •
Coordination of lithium ion with two carbonyl groups is proposed.