Ionotropic glutamate receptor expression in human white matter
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- 作者：Pia Crone Christensen ; PhDa ; Zahra Samadi-Bahrami ; PhDb ; Vlady Pavlov ; BMLScb ; Peter K. Stys ; MD FRCP(C)a ; pstys@ucalgary.ca" class="auth_mail" title="E-mail the corresponding author ; G.R. Wayne Moore ; MD CM FRCP(C) FRCPathb
- 关键词：(AMPA) ; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid ; (CNS) ; central nervous system ; (DAPI) ; 4&prime ; 6-diamidino-2-phenylindole ; (GABA) ; gamma-aminobutyric acid ; (iGluR) ; ionotropic glutamate receptor ; (MBP) ; myelin basic protein ; (MS) ; multiple sclerosis ; (NMDA) ; N-Methyl-d-Aspartic Acid ; (OPC) ; oligodendrocyte precursor cell ; (WM) ; white matter
- 刊名：Neuroscience Letters
- 出版年：2016
- 出版时间：6 September 2016
- 年：2016
- 卷：630
- 期：Complete
- 页码：1-8
- 全文大小：2842 K
文摘
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iGluRs are expressed in normal human white matter.
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AMPA receptor subunit GluA4 is expressed on oligodendrocytes, myelin and on axons.
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NMDA receptor subunit GluN1 is expressed on oligodendrocytes and myelin.
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Results confirm findings reported in the literature from rodent white matter.