Light induced structural changes of the photoprotein mnemiopsin: Characterization and contribution in photoinactivation

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• 作者：Zaiddodine Pashandi^a ; Maryam Molakarimi^b ; Reza H. Sajedi^b ; ^{sajedi_r@modares.ac.ir} ; Majid Taghdir^a ; Hossein Naderi-Manesh^a ; ^{naderman@modares.ac.ir}
• 关键词：Photoprotein ; Mnemiopsin ; Aequorin ; Photoinactivation ; Light induced structural changes
• 刊名：Journal of Photochemistry and Photobiology B: Biology
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：165
• 期：Complete
• 页码：133-140
• 全文大小：1427 K
• 卷排序：165

文摘

Mnemiopsin and aequorin display increased flexibility in structure due to light. Exposure to the light induce more vigorous tertiary structural disorders than Ca2 +. Mnemiopsin unlike aequorin displays reduction in helical contents due to light. Light induced structural changes is independent of presence of coelenterazine. Photoinactivation is originating from coelenterazine binding cavity.