Reduced respiratory neural activity elicits a long-lasting decrease in the CO2 threshold for apnea in anesthetized rats
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- 作者：N.A. Baertsch ; T.L. Baker ; bakert@svm.vetmed.wisc.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：aCSF ; artificial cerebrospinal fluid ; AT ; apneic threshold ; CHF ; chronic heart failure ; CRSD ; Charles River Sprague Dawley ; CSA ; central sleep apnea ; ETCO2 ; end-tidal CO2 ; HSD ; Harlan Sprague Dawley ; iPMF ; inactivity-induced phrenic motor facilitation ; OSA ; obstructive sleep apnea ; pLTF ; phrenic long-term facilitation ; RT ; recruitment threshold
- 刊名：Experimental Neurology
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：287
- 期：part_P2
- 页码：235-242
- 全文大小：999 K
文摘
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Repeated central neural apneas progressively decrease the apneic threshold.
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Intermittent and prolonged neural apneas elicit iPMF, a form of spinal plasticity.
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Long-lasting decreases in the apneic threshold are associated with iPMF.
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Prolonged neural apneas transiently decrease the recruitment threshold.
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Decreases in the recruitment threshold are not associated with iPMF.