Regulation of hypothalamic-pituitary-adrenal axis activity and immunologic function contributed to the anti-inflammatory effect of acupuncture in the OVA-induced murine asthma model

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• 作者：Ying Wei^a ; ^b ; ¹ ; Ming Dong^c ; ¹ ; Ling Zhong^d ; Jiaqi Liu^a ; ^b ; Qingli Luo^a ; ^b ; Yubao Lv^a ; ^b ; Shuming Mo^a ; ^b ; Jing Sun^a ; ^b ; Feng Liu^a ; ^b ; Fei Xu^a ; ^b ; Chen Yan^a ; ^b ; Jingcheng Dong^a ; ^b ; ^{jcdong2004@126.com}
• 关键词：Acupuncture ; Asthma ; Inflammation ; Immunologic function ; HPA axis
• 刊名：Neuroscience Letters
• 出版年：2017
• 出版时间：1 January 2017
• 年：2017
• 卷：636
• 期：Complete
• 页码：177-183
• 全文大小：1555 K
• 卷排序：636

文摘

We evaluated the regulatory role of acupuncture in airway inflammation and the HPA axis activity in murine asthma model. Our results demonstrated that acupuncture was effective in suppression of AHR and airway inflammation in serum. The HPA axis activity was regulated by acupucnture. Our findings may provide support to better understand the contribution of acupuncture to regulation of inflammation and HPA axis activity in asthma.