Effects of plateletpheresis on blood coagulation parameters in healthy donors at National Blood Centre, Kuala Lumpur, Malaysia
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- 作者：A.K. Siti Nadiah ; M. Nor Asiah ; A.T. Nur Syimah ; M. Normi ; E. Anza ; A. Nor Aini ; T.H. Mohd Zahari ; M. Shahnaz ; A.K. Faraizah ; M.A. Faisal
- 关键词：Platelet ; Apheresis ; Blood coagulation ; Plateletpheresis ; Cell separator
- 刊名：Transfusion and Apheresis Science
- 出版年：December, 2013
- 年：2013
- 卷：49
- 期：3
- 页码：507-510
- 全文大小：240 K
文摘
Plateletpheresis is a method used to remove platelet from the body either from random volunteer donors, patient鈥檚 family members or HLA matched donors. A cross sectional study was carried out on 59 plateletpheresis donors aged between 18 and 55 years at National Blood Center (NBC), Kuala Lumpur. We compared the blood parameters before and after plateletpheresis and we found that the platelet count, FVIII, fibrinogen and thrombophilia markers anti-thrombin (AT), protein C and protein S were significantly reduced (p < 0.05) with prolonged PT and APTT. There were significant changes in blood coagulation parameters but it is within acceptable range.