High-level JCPyV viruria after kidney transplantation—Clinical and histopathological findings

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• 作者：Ilkka Helanterä ; ^a ; ^{Ilkka.helantera@helsinki.fi} ; Hans H. Hirsch^b ; ^c ; Eeva Auvinen^d ; Laura Mannonen^d ; Maaret Nummi^d ; Marion Wernli^b ; Fernanda Ortiz^e ; Anne Rä ; isä ; nen-Sokolowski^f ; Marko Lempinen^a ; Irmeli Lautenschlager^d
• 关键词：CADI ; chronic allograft damage index ; eGFR ; estimated glomerular filtration rate ; BKPyV ; BK polyomavirus ; JCPyV ; JC polyomavirus ; PML ; progressive multifocal leukoencephalopathy ; PyVAN ; polyomavirus-associated nephropathy
• 刊名：Journal of Clinical Virology
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：85
• 期：Complete
• 页码：75-79
• 全文大小：408 K
• 卷排序：85

文摘

High-level JCPyV replication is seen in less than 10% of patients after kidney transplantation. Patients who are JCPyV seronegative before transplantation seem to be at a higher risk of high-level JCPyV viruria after transplantation. High-level JCPyV viruria is not associated with inferior graft function or survival in long-term follow-up. High-level JCPyV viruria was not associated with histopathological changes in protocol biopsies.