Expression analysis of cytosolic DNA-sensing pathway genes in the intestinal mucosal layer of necrotic enteritis-induced chicken
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- 作者：Deivendran Rengaraja ; deivendran@cau.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Anh Duc Truonga ; truonganhduc84@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Sung-Hyen Leeb ; lshin@korea.kr" class="auth_mail" title="E-mail the corresponding author ; Hyun S. Lillehojc ; Hyun.Lillehoj@ars.usda.gov" class="auth_mail" title="E-mail the corresponding author ; Yeong Ho Honga ; yhong@cau.ac.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：POLR2F ; polymerase (RNA) II (DNA directed) polypeptide F ; POLR3A ; polymerase (RNA) III (DNA directed) polypeptide A ; 155 ; kDa ; POLR3B ; polymerase (RNA) III (DNA directed) polypeptide B ; MAVS ; mitochondrial antiviral signaling protein ; RELA ; v-rel avian reticuloendotheliosis viral oncogene homolog A ; TMEM173 ; transmembrane protein 173 ; ADAR ; adenosine deaminase ; RNA-specific ; IFNB ; interferon beta 1 ; NFKBIB ; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor ; beta ; C
- 刊名：Veterinary Immunology and Immunopathology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：170
- 期：Complete
- 页码：1-12
- 全文大小：2550 K
文摘
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Nectotic enteritis was induced in two genetically disparate chicken lines.
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RNA-sequencing was performed in the intestinal mucosa of NE-induced chickens.
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Differentially expressed genes status in cytosolic DNA-sensing pathway was analyzed.
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Cytosolic DNA-sensing pathway genes were examined by real time qPCR.
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Results indicate that necrotic enteritis affects foreign DNA sensing mechanisms.